NBextensions and compatibility of extentions

Hi all!
I am working on a clean environment rebuild using miniconda vs the full anaconda distro. It’s going great so far in terms of managing dep issues however… i’m getting an interesting response when configuring extensions. essentially i get the message (see below) that some extensions may be incompatible so they are turned off by default. But with that checked EVERYTHING is unvailable to me to turn on / customize. (for example i can’t check scratchpad to turn it on in the notebook nor can i check autopep8"

if i uncheck that message, i can then use the extensions and configure as i’d like.
what does that message mean? are there install steps that i could do to avoid it and ensure compatible extensions?

Thank you for any suggestions,